Linker for activation of T cells (LAT) is a central adaptor protein in proximal T cell activation.A key element of its adaptor function is the efficiency with which LAT interacts with its binding partners.Such efficiency is Cup and Saucer controlled by the local concentration of LAT as well as the vicinity to up- and downstream interaction partners
Objective During the operation of urban rail transit trains, incidents such as collisions, derailments and overturning may occur.It is essential to study the dynamic behavior of trains and the technology to prevent overturning under these conditions.Method Combining the actual vehicle windshield structure and vehicle dynamic envelope during operati
Subgraph matching, which involves identifying a query graph Collections within a larger data graph, is a fundamental problem that has applications in various fields.Although graph neural networks (GNNs) are commonly used in learning-based subgraph matching, they face challenges due to their convolution process.Specifically, GNNs generate new node f
This article gives a comparative analysis of theological and political views of two most important representatives of the Nicene party at the fi nal stage of the Arian controversy, namely St.Damasus of Rome and St.Gregory the Theologian.The article points out the coincidence of views of the two bishops on the problem of the Antiochian schism, but t